Blue 2 (Indigo Carmine)

Also known as: Indigotine, FD&C Blue No. 2, CI 73015

Color additive · E132

Regulatory Status

United States (FDA)

Approved

FDA-approved. Also used as diagnostic dye in medical procedures.

European Union (EFSA)

Approved

Approved in EU. ADI: 5 mg/kg body weight/day.

Safety Profile

Generally considered safe at food-use levels. The medical community uses it as a diagnostic dye, which provides additional safety data.

Health Concerns

  • • Some animal studies show brain tumors at extremely high doses
  • • Poor absorption limits concern
  • • May cause nausea at high concentrations

Commonly Found In

CandyBeveragesDog foodMedical diagnostics

Sources: FDA Substances Added to Food, EFSA opinions, EU Regulation 1333/2008, IARC monographs

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.