Acetaminophen, Caffeine, Pyrilamine Maleate: Uses, Side Effects, and Drug Interactions

Brand names: Buscapina

# Pain Relief and Sleep Aid Combination This medicine contains three active ingredients that work together to help you feel better. Acetaminophen reduces pain and fever, caffeine helps boost the medicine's effectiveness and can reduce drowsiness, and pyrilamine maleate is an antihistamine that helps you sleep. People use this combination when they have minor aches, pains, or headaches and need help sleeping at the same time. It's commonly taken before bed when pain is keeping someone awake. Before using this medicine, you should know some important safety rules. Don't take it if you're allergic to any of the ingredients, and never give it to children without talking to a doctor first. While taking this medicine, avoid alcohol and other drugs that contain acetaminophen, since too much can damage your liver. If you're pregnant, breastfeeding, or taking other medications, ask your doctor before using it. Stop taking the medicine and call a doctor if you have serious side effects like severe allergic reactions, yellowing of the skin, or unusual bruising. Always follow the dosage instructions on the package and store the medicine safely away from children.

Taking Acetaminophen, Caffeine, Pyrilamine Maleate with other medications?

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Most Reported Side Effects (FAERS)

  • ABDOMINAL PAIN22 reports
  • VOMITING22 reports
  • DIARRHOEA18 reports
  • NAUSEA18 reports
  • MUCOSAL INFLAMMATION15 reports
  • PAIN15 reports
  • ABDOMINAL PAIN UPPER14 reports
  • ASTHENIA14 reports
  • INSOMNIA13 reports
  • DIZZINESS12 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.