Acetaminophen Chlorpheniramine Maleate Dextromethorphan Hydrobromide Phenylepherine Hydrochloride: Uses, Side Effects, and Drug Interactions

Brand names: Cough and Cold XL3 Xtra

# Overview of This Cold and Flu Medicine This medicine is a combination drug that treats multiple cold and flu symptoms at the same time. It contains four active ingredients that work together: acetaminophen reduces fever and pain, chlorpheniramine maleate dries up a runny nose and stops sneezing, dextromethorphan hydrobromide stops coughing, and phenylephrine hydrochloride clears nasal congestion. People use this medication when they have several cold or flu symptoms happening together, like a cough, stuffy nose, runny nose, fever, body aches, and sneezing. It's designed to help you feel better while your body fights off the illness. Before taking this medicine, it's important to follow the dosage instructions carefully and know what to avoid. Never use this drug if you're allergic to any of its ingredients or if you're taking other medications that contain similar ingredients, since you could take too much by accident. Don't give this medicine to very young children, and always keep it out of reach of small kids. Stop using the medicine and call your doctor if your symptoms don't improve after a few days or if you develop new problems. If you have serious health conditions like heart disease or high blood pressure, talk to your doctor before using this medicine to make sure it's safe for you.

Taking Acetaminophen Chlorpheniramine Maleate Dextromethorphan Hydrobromide Phenylepherine Hydrochloride with other medications?

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Most Reported Side Effects (FAERS)

  • ASTHENIA1 reports
  • BALANCE DISORDER1 reports
  • BEDRIDDEN1 reports
  • DECREASED APPETITE1 reports
  • FEEDING DISORDER1 reports
  • MALAISE1 reports
  • MUSCULAR WEAKNESS1 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

Check interactions with Acetaminophen Chlorpheniramine Maleate Dextromethorphan Hydrobromide Phenylepherine Hydrochloride:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.