Acetaminophen Dextromethorphan Hydrobromide Doxylamine Succinate: Uses, Side Effects, and Drug Interactions

Brand names: Night Time Cold and Flu

# Nighttime Cold and Flu Relief Medicine This medicine is a combination of three active ingredients that work together to help you feel better when you have a cold or flu. Acetaminophen reduces fever and pain, dextromethorphan stops your cough, and doxylamine helps you sleep better at night. People usually take this medicine in the evening before bed because it's designed to help you rest while treating cold and flu symptoms. It's important to only take the amount recommended on the package and not to use it for more than a few days without talking to a doctor. Before taking this medicine, you should know some important safety rules. Don't use it if you're allergic to any of the ingredients, and always keep it away from children since it can be dangerous to them. If you're pregnant, nursing a baby, or taking other medicines, ask your doctor first. Stop using this medicine and call a doctor if you have serious side effects or if your symptoms don't improve. Never combine this medicine with other products that contain acetaminophen, as this could cause harm. Store the medicine at room temperature in a safe place, and always read the label carefully before taking it.

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Most Reported Side Effects (FAERS)

  • COVID-19174 reports
  • DISEASE RECURRENCE135 reports
  • NASOPHARYNGITIS123 reports
  • FATIGUE104 reports
  • COUGH100 reports
  • NAUSEA92 reports
  • DRUG INEFFECTIVE82 reports
  • DIZZINESS78 reports
  • DIARRHOEA76 reports
  • VOMITING75 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

Check interactions with Acetaminophen Dextromethorphan Hydrobromide Doxylamine Succinate:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.