Allopurinol: Uses, Side Effects, and Drug Interactions
Brand names: Allopurinol
# Allopurinol Overview Allopurinol is a medicine used to treat gout and prevent kidney stones by lowering uric acid levels in your body. When you have too much uric acid, it can form crystals in your joints and kidneys, causing pain and other problems. This medication works by reducing the amount of uric acid your body makes. Doctors may prescribe it for people who have gout attacks, high uric acid levels, or certain types of cancer that can cause kidney problems. While allopurinol is helpful for many people, there are important safety things to know. Some antibiotics and water pills can increase your risk of serious skin reactions when taken with allopurinol, so tell your doctor about all medicines you're taking. Never use allopurinol with certain cancer medicines like capecitabine or pegloticase without talking to your doctor first, as they may need to adjust your dose or choose a different medicine. Always follow your doctor's instructions carefully and report any unusual skin rashes, fevers, or side effects right away, especially when you first start taking this medication.
Taking Allopurinol with other medications?
Check Allopurinol against any other medication — the form below is already pre-filled.
Check Now ↓Most Reported Side Effects (FAERS)
- DIARRHOEA8,445 reports
- FATIGUE7,994 reports
- DYSPNOEA7,702 reports
- NAUSEA7,078 reports
- DEATH6,683 reports
- ACUTE KIDNEY INJURY6,571 reports
- OFF LABEL USE6,301 reports
- PYREXIA5,982 reports
- PNEUMONIA5,594 reports
- ASTHENIA5,511 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (2)
- Class II
Dr. Reddy's Laboratories, Inc. · June 7, 2024
Allopurinol Tablets, USP 300mg, 100 Tablets per bottle, Rx only, Manufactured By: Dr. Reddy's Laboratories LA LLC, Shreveport, LA 71106 USA, NDC 55111-730-01.Presence of foreign substance.
- Class II
CARDINAL HEALTHCARE · January 26, 2022
ALLOPURINOL Tablets, USP 300 MG 500 count Tablets per bottle, Rx only, Manufactured By: Dr. Reddy's Laboratories LA LLC, Shreveport, LA 71106. NDC: 55111-730-05CGMP Deviations: Products were exposed to temperatures outside of the products labeled storage conditions.
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Check interactions with Allopurinol:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.