Amlodipine: Uses, Side Effects, and Drug Interactions
Brand names: Amlodipine Besylate
# Overview of Amlodipine Amlodipine is a medication used to treat high blood pressure and certain types of chest pain called angina. It works by relaxing blood vessels and improving blood flow, which helps your heart work more efficiently and lowers your blood pressure. Doctors prescribe amlodipine to help reduce your risk of heart attack and stroke. It comes in tablet form and you typically take it once a day by mouth, with or without food. Like all medicines, amlodipine can cause side effects and may interact with other drugs you're taking. It's important to tell your doctor about all medications and supplements you use, especially simvastatin and certain other drugs that can increase amlodipine's effects in your body. Common side effects include swelling in your feet or ankles and dizziness. You should not stop taking amlodipine without talking to your doctor first, even if you feel better, because it works best when taken regularly. If you have any questions or concerns about this medication, always ask your doctor or pharmacist.
Known Interactions (6)
Taking Amlodipine with other medications?
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Check Now ↓Most Reported Side Effects (FAERS)
- FATIGUE25,703 reports
- DIARRHOEA22,375 reports
- NAUSEA22,237 reports
- DYSPNOEA21,220 reports
- DRUG INEFFECTIVE20,012 reports
- DIZZINESS18,101 reports
- HEADACHE16,755 reports
- OFF LABEL USE16,578 reports
- PAIN16,046 reports
- ASTHENIA14,643 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (2)
- Class II
Ascend Laboratories, LLC · July 21, 2025
Amlodipine and Olmesartan Medoxomil Tablets, 5 mg/ 40 mg, 30-count bottle, Rx Only, Manufactured by: Alkem Laboratories Ltd., INDIA; Distributed by: Ascend Laboratories, LLC, Parsippany, NJ 07054, NDCFailed Dissolution Specifications: low dissolution results
- Class II
Lupin Pharmaceuticals Inc. · July 2, 2025
Amlodipine and Benazepril HCl Capsules USP 2.5 mg/10 mg, 100 Capsules bottle, Rx Only, Manufactured for: Lupin Pharmaceuticals, Inc., Naples, FL, 34108, United States, Manufactured by: Lupin Limited,Labeling: Incorrect or Missing Lot and/or Exp Date: released with wrong expiry date as Feb.2027 instead of Jan.2027
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Supplement Interactions (1)
These dietary supplements may interact with Amlodipine. Always consult your healthcare provider.
- mildmelatonin
Melatonin may enhance the blood pressure-lowering effect of antihypertensives.
Monitor blood pressure when starting melatonin.
Check interactions with Amlodipine:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.