Aripiprazole: Uses, Side Effects, and Drug Interactions

Brand names: Aripiprazole

# Overview of Aripiprazole Aripiprazole is a prescription medicine used to treat certain mental health conditions. It helps people who have schizophrenia, bipolar disorder, or depression that doesn't get better with other medicines. Doctors also prescribe it for irritability in children with autism. This medication works by helping balance chemicals in the brain called neurotransmitters, which affect mood, thoughts, and behavior. When taking aripiprazole, it's important to know some safety information. This medicine can cause serious side effects in some people, which is why it comes with a boxed warning—the FDA's strongest safety alert. You should never stop taking this medicine suddenly without talking to your doctor first, even if you feel better. If you're taking other medications, tell your doctor because aripiprazole can interact with certain drugs, and your dose might need to be adjusted. It's especially important to mention this to your doctor if you're pregnant, planning to become pregnant, or taking other medicines that affect how your body processes aripiprazole.

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Most Reported Side Effects (FAERS)

  • DRUG INEFFECTIVE8,306 reports
  • OFF LABEL USE8,299 reports
  • WEIGHT INCREASED7,873 reports
  • PRODUCT USE IN UNAPPROVED INDICATION5,252 reports
  • ANXIETY5,109 reports
  • FATIGUE4,318 reports
  • DEPRESSION4,051 reports
  • SUICIDAL IDEATION4,036 reports
  • NAUSEA3,974 reports
  • INSOMNIA3,890 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

Recent Recalls (5)

Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.