atomoxetine

Brand names: Atomoxetine

# Atomoxetine Overview Atomoxetine is a medication used to treat attention-deficit/hyperactivity disorder (ADHD) in children, teenagers, and adults. It works by helping the brain focus better and control impulses by increasing certain chemicals that help with attention and concentration. Unlike some other ADHD medications, atomoxetine is not a stimulant. It comes in capsule form and is usually taken once or twice a day by mouth. A doctor will determine the right dose for each person based on their age and weight. There are some important safety things to know about atomoxetine. People taking this medicine should tell their doctor about all other medications they're taking, especially blood pressure medicines, asthma inhalers, and certain antidepressants, because atomoxetine can interact with these drugs. It's important to have your blood pressure checked regularly while taking this medication. Some people may experience side effects like stomach problems, dizziness, or trouble sleeping, and you should report any unusual symptoms to your doctor right away. Never mix atomoxetine with certain medicines called MAOIs, and always follow your doctor's dosage instructions carefully.

Known Interactions

7 DRUG INTERACTIONS • Monoamine Oxidase Inhibitors. ( 4.2 , 7.1 ) • CYP2D6 Inhibitors - Concomitant use may increase atomoxetine steady-state plasma concentrations in EMs. ( 7.2 ) • Antihypertensive Drugs and Pressor Agents – Possible effects on blood pressure. ( 7.3 ) • Albuterol (or other beta 2 agonists) - Action of albuterol on cardiovascular system can be potentiated. ( 7.4 ) 7.1 Monoamine Oxidase Inhibitors With other drugs that affect brain monoamine concentrations, there have been reports of serious, sometimes fatal reactions (including hyperthermia, rigidity, myoclonus, autonomic instability with possible rapid fluctuations of vital signs, and mental status changes that include extreme agitation progressing to delirium and coma) when taken in combination with an MAOI. Some cases presented with features resembling neuroleptic malignant syndrome. Such reactions may occur when these drugs are given concurrently or in close proximity [see Contraindications ( 4.2 )]. 7.2 Effect of

Source: FDA-approved drug labeling via openFDA

Most Reported Side Effects (FAERS)

  • DRUG INEFFECTIVE2,838 reports
  • NAUSEA2,162 reports
  • FATIGUE2,137 reports
  • HEADACHE1,750 reports
  • VOMITING1,720 reports
  • OFF LABEL USE1,692 reports
  • DIZZINESS1,598 reports
  • INSOMNIA1,561 reports
  • SOMNOLENCE1,447 reports
  • DEPRESSION1,381 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

Check interactions with atomoxetine:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.