enalapril

Brand names: Enalapril Maleate

# Overview of Enalapril Enalapril is a medication used to treat high blood pressure and heart failure. It works by relaxing blood vessels, which helps blood flow more easily through your body and reduces the pressure on your heart. This means your heart doesn't have to work as hard to pump blood, and your blood pressure goes down. Doctors often prescribe enalapril to help prevent heart attacks and strokes in people whose blood pressure is too high. Before taking enalapril, it's important to know some safety information. You should tell your doctor if you're pregnant, planning to become pregnant, or breastfeeding, because this medicine can harm an unborn baby. Don't take enalapril with certain other blood pressure medicines, as combining them can be dangerous and may cause kidney problems or dangerously high potassium levels. Some people may have an allergic reaction that causes serious swelling, so contact your doctor right away if you notice any unusual symptoms. Always take enalapril exactly as your doctor prescribes and keep all your doctor's appointments so they can monitor how well the medicine is working for you.

Known Interactions

Drug Interactions Neprilysin Inhibitors Patients taking concomitant neprilysin inhibitors may be at increased risk for angioedema (see WARNINGS ). Dual Blockade of the Renin-Angiotensin System (RAS) Dual blockade of the RAS with angiotensin receptor blockers, ACE inhibitors, or aliskiren is associated with increased risks of hypotension, hyperkalemia, and changes in renal function (including acute renal failure) compared to monotherapy. Most patients receiving the combination of two RAS inhibitors do not obtain any additional benefit compared to monotherapy. In general, avoid combined use of RAS inhibitors. Closely monitor blood pressure, renal function, and electrolytes in patients on enalapril maleate and other agents that affect the RAS. Do not coadminister aliskiren with enalapril maleate in patients with diabetes. Avoid use of aliskiren with enalapril maleate in patients with renal impairment (GFR <60 mL/min). Hypotension — Patients on Diuretic Therapy Patients on diuretics and es

Source: FDA-approved drug labeling via openFDA

Most Reported Side Effects (FAERS)

  • DIARRHOEA3,113 reports
  • DYSPNOEA2,995 reports
  • NAUSEA2,990 reports
  • DRUG INEFFECTIVE2,847 reports
  • FATIGUE2,669 reports
  • DIZZINESS2,526 reports
  • DRUG INTERACTION2,434 reports
  • VOMITING2,220 reports
  • PAIN2,104 reports
  • ACUTE KIDNEY INJURY2,087 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

Check interactions with enalapril:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.