Esomeprazole: Uses, Side Effects, and Drug Interactions
Brand names: Acid Reducer
# Overview of Esomeprazole Esomeprazole is a medicine that helps reduce the amount of acid your stomach makes. Doctors prescribe it to treat heartburn, acid reflux, and stomach ulcers. When you have acid reflux, stomach acid backs up into your food pipe and causes a burning feeling in your chest. Esomeprazole works by blocking the parts of your stomach that produce acid, which gives your stomach and food pipe time to heal and feel better. Before taking esomeprazole, it's important to know some safety rules. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, since this medicine might affect your baby. Don't give this medicine to children unless a doctor says it's okay. You should also talk to your doctor before taking esomeprazole if you have liver problems or take other medicines regularly. Take this medication exactly as your doctor tells you to—usually by swallowing the pill whole with water. If you have any questions or notice side effects while taking esomeprazole, stop taking it and call your doctor right away.
Taking Esomeprazole with other medications?
Check Esomeprazole against any other medication — the form below is already pre-filled.
Check Now ↓Most Reported Side Effects (FAERS)
- CHRONIC KIDNEY DISEASE35,572 reports
- ACUTE KIDNEY INJURY20,390 reports
- RENAL FAILURE16,261 reports
- DRUG INEFFECTIVE14,115 reports
- NAUSEA13,295 reports
- GASTROOESOPHAGEAL REFLUX DISEASE11,930 reports
- DRUG DOSE OMISSION11,128 reports
- DIARRHOEA11,061 reports
- PAIN10,643 reports
- END STAGE RENAL DISEASE10,295 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (3)
- Class II
Zydus Pharmaceuticals (USA) Inc · May 13, 2025
Esomeprazole Magnesium for Delayed-Release Oral Suspension, 20 mg, 30-count single dose packets per carton, Rx Only, Manufactured by: Zydus Lifesciences Ltd. Ahmedabad, India, Distributed by: Zydus PhFailed Impurities/Degradation Specifications: Out-of-Specification test results obtained for any individual unknown degradation product during Related Compounds testing during long term stability.
- Class II
Zydus Pharmaceuticals (USA) Inc · May 13, 2025
Esomeprazole Magnesium for Delayed-Release Oral Suspension, 40 mg, 30-count Single-Dose Packets per carton, Rx Only, Manufactured by: Zydus Lifesciences Ltd. Ahmedabad, India, Distributed by: Zydus PhFailed Impurities/Degradation Specifications: Out-of-Specification test results obtained for any individual unknown degradation product during Related Compounds testing during long term stability.
- Class III
Zydus Pharmaceuticals (USA) Inc · November 14, 2024
Esomeprazole Magnesium for Delayed-Release Oral Suspension 40 mg, 30 Single-Dose Packets, Rx Only, Manufactured by: Zydus Lifesciences Ltd. Ahmedabad, India, Distributed by: Zydus Pharmaceuticals (USALabeling: Not Elsewhere Classified - Wrong NDC number
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Check interactions with Esomeprazole:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.