furosemide

Brand names: Furosemide

# Furosemide: What You Need to Know Furosemide is a water pill that helps your body get rid of extra fluid and salt through urine. Doctors prescribe it to treat conditions like high blood pressure, heart disease, and kidney problems where your body holds onto too much fluid. When you take furosemide, you'll notice you need to urinate more often than usual. This helps reduce swelling and makes it easier for your heart to pump blood throughout your body. While furosemide is helpful, there are some important safety things to remember. You should never mix this medicine with certain other drugs, especially antibiotics and other water pills, because they can damage your hearing. If you're taking aspirin for pain or rheumatism, tell your doctor before taking furosemide, since the combination can cause problems. Make sure to get regular blood tests while using this medicine, and always take it exactly as your doctor prescribes. If you notice any hearing loss, dizziness, or signs of weakness, contact your doctor right away.

Known Interactions

Drug Interactions Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Except in life-threatening situations, avoid this combination. Furosemide should not be used concomitantly with ethacrynic acid because of the possibility of ototoxicity. Patients receiving high doses of salicylates concomitantly with furosemide, as in rheumatic disease, may experience salicylate toxicity at lower doses because of competitive renal excretory sites. There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as cisplatin may be enhanced if furosemide is not given in lower doses and with positive fluid balance when used to achieve forced diuresis during cisplatin treatment. Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine. Lithium generally should not

Source: FDA-approved drug labeling via openFDA

Most Reported Side Effects (FAERS)

  • DYSPNOEA29,109 reports
  • FATIGUE20,395 reports
  • DIARRHOEA19,939 reports
  • NAUSEA18,690 reports
  • ACUTE KIDNEY INJURY18,531 reports
  • DEATH18,325 reports
  • FALL16,156 reports
  • PNEUMONIA16,080 reports
  • ASTHENIA15,175 reports
  • HYPOTENSION14,759 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

Check interactions with furosemide:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.