Guaifenesin: Uses, Side Effects, and Drug Interactions
Brand names: Rompe Pechito DM for Kids
# Guaifenesin Overview Guaifenesin is a medicine that helps your body get rid of mucus when you have a cough caused by a cold, flu, or bronchitis. When you're sick, your body makes extra thick mucus in your chest and throat. This medicine makes that mucus thinner and easier to cough up, so you can clear your airways and feel better. It's often found in over-the-counter cough medicines that you can buy at any pharmacy without a prescription. When using guaifenesin, it's important to follow the dosage instructions on the package for your age and always check with a doctor if you have other health conditions or take other medicines. Keep this medicine out of reach of children and only give it to kids if the label says it's safe for their age. If your cough lasts for more than a week, gets worse, or you start coughing up blood, you should stop taking the medicine and talk to a doctor right away. Remember to drink plenty of water while taking this medicine because it works better when you stay hydrated.
Taking Guaifenesin with other medications?
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Check Now ↓Most Reported Side Effects (FAERS)
- DRUG INEFFECTIVE21,635 reports
- FATIGUE18,206 reports
- NAUSEA15,124 reports
- HEADACHE14,940 reports
- PAIN14,277 reports
- DIARRHOEA13,403 reports
- OFF LABEL USE12,964 reports
- DYSPNOEA12,333 reports
- ARTHRALGIA10,782 reports
- DIZZINESS9,934 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (4)
- Class III
PAI Holdings, LLC. dba Pharmaceutical Associates Inc · January 7, 2025
Guaifenesin and Codeine Phosphate Oral Solution USP, 100mg/10 mg per 5 mL, 16 fl oz (473 ml) bottles, PAI Pharmaceutical Associates, Inc., Greenville, SC 29605, NDC 0121-0775-16Superpotent; sodium benzoate preservative
- Class II
LNK International, Inc. · November 14, 2024
Kirkland Severe Cold & Flu Plus Congestion: Day - 112 coated caplets blister pack; (Acetaminophen 325mg, Dextromethorphan HBr 10 mg, Guaifenesin 200 mg, Phenylephrine HCl 5 mg); Night - 56 coated caplCGMP Deviations: Released product should have been rejected.
- Class III
Denison Pharmaceuticals, LLC · September 25, 2024
Adult Cough and Chest Congestion (Dextromethorphan HBr USP 20 mg, Guaifenesin USP 400mg), packaged in 4 oz bottles further package in cartons, Distributed by: Genexa Inc., Alanta, GA, 30318, NDC-696Crystallization: Lack of uniformity - a change in texture, chunky, grainy, and small crystal substances inside the bottles.
- Class III
Denison Pharmaceuticals, LLC · September 25, 2024
Kids' Cough and Chest Congestion (Dextromethorphan HBr, USP 5mg/ Guaifenesin, USP 100 mg), packaged in 4 oz bottles further packaged in cartons, Distributed by: Genexa Inc., Alanta, GA, 30318, NDC-696Crystallization: Lack of uniformity - a change in texture, chunky, grainy, and small crystal substances inside the bottles.
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Check interactions with Guaifenesin:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.