irbesartan
Brand names: Irbesartan
# Irbesartan Overview Irbesartan is a medication used to treat high blood pressure and to protect the kidneys in people with diabetes who have high blood pressure. It works by relaxing blood vessels so blood can flow more easily, which helps lower your blood pressure. This medicine helps prevent serious problems like heart attacks and strokes caused by high blood pressure. Your doctor will determine the right dose for you based on your individual health needs. When taking irbesartan, it's important to know about some safety concerns. Don't take this medicine if you're pregnant, as it can harm your baby. Tell your doctor about all other medicines you take, especially pain relievers like ibuprofen, medicines containing lithium, or other blood pressure medications—these combinations can cause serious side effects. Your doctor may need to check your kidney function and potassium levels with blood tests while you're on this medication. Like all medicines, irbesartan can cause side effects, so report any unusual symptoms to your doctor right away.
Known Interactions
7 DRUG INTERACTIONS Lithium: Risk of lithium toxicity. ( 7 ) Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and COX-2 inhibitors: Increased risk of renal impairment. Reduced antihypertensive effects. ( 7 ) Dual blockade of the renin-angiotensin system: Increased risk of renal impairment, hypotension, and hyperkalemia. ( 7 ) 7.1 Agents Increasing Serum Potassium Coadministration of irbesartan tablets with other drugs that raise serum potassium levels may result in hyperkalemia, sometimes severe. Monitor serum potassium in such patients. 7.2 Lithium Increases in serum lithium concentrations and lithium toxicity have been reported with concomitant use of irbesartan and lithium. Monitor lithium levels in patients receiving irbesartan and lithium. 7.3 Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors) In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministr
Source: FDA-approved drug labeling via openFDA
Most Reported Side Effects (FAERS)
- NAUSEA2,746 reports
- FATIGUE2,730 reports
- DIARRHOEA2,454 reports
- DRUG INEFFECTIVE2,403 reports
- DIZZINESS2,300 reports
- DYSPNOEA2,205 reports
- ACUTE KIDNEY INJURY2,118 reports
- HEADACHE2,092 reports
- FALL2,084 reports
- ASTHENIA1,850 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Check interactions with irbesartan:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.