Ketorolac: Uses, Side Effects, and Drug Interactions
Brand names: Ketorolac Tromethamine
# Ketorolac Overview Ketorolac is a strong pain reliever that doctors prescribe for moderate to severe pain, usually after surgery or an injury. It works by reducing swelling and pain in your body. Unlike some pain medicines, ketorolac works quickly and doesn't make you feel sleepy. This medicine is typically only used for a short time—usually no more than 5 days—because it's not meant to be taken for long periods. Since ketorolac is a powerful medication, it comes with important safety warnings. It can cause serious problems with your stomach, including ulcers and bleeding, especially if you take it for too long or have stomach issues already. This medicine can also affect your heart and kidneys, so doctors need to make sure it's safe for you before prescribing it. You should never take ketorolac if you're allergic to it, and you should tell your doctor about any other health conditions you have or medicines you're taking. Always take ketorolac exactly as your doctor directs and for the shortest time possible to stay safe.
Taking Ketorolac with other medications?
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Check Now ↓Most Reported Side Effects (FAERS)
- DRUG INEFFECTIVE560 reports
- DRUG HYPERSENSITIVITY323 reports
- NAUSEA281 reports
- HEADACHE272 reports
- PAIN272 reports
- FATIGUE245 reports
- DYSPNOEA238 reports
- OFF LABEL USE230 reports
- TREATMENT FAILURE213 reports
- EYE PAIN205 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (3)
- Class II
Aspiro Pharma Limited · October 1, 2025
Ketorolac Tromethamine Injection, USP, 60 mg/2 mL (30 mg/mL), 2 mL Single-Dose Vial, For Intramuscular Use Only, Rx only, Mfd. for: Camber Pharmaceuticals, Inc., Piscataway, NJ 08854, Mfd. by: ASPIROPresence of Particulate Matter: Particulate matter identified as glass
- Class II
Apotex Corp. · September 5, 2025
Ketorolac Tromethamine Ophthalmic Solution, 0.5%, 5 mL, Rx Only, Sterile, Manufactured by: Apotex Inc., Richmond Hill, Ontario, Canada, L4C 5H2, Manufactured for: Apotex Corp., Weston, FL 33326, NDC 6Lack of Assurance of Sterility; atypical weight loss due to improper bottle sealing leading to potential sterility concerns
- Class II
Apotex Corp. · May 28, 2025
Ketorolac Tromethamine Ophthalmic Solution, 0.5%, 10 mL, Rx Only, Manufactured by: Apotex Inc., Toronto, Ontario, Canada, M9L 1T9, Manufactured for: Apotex Corp., Weston, FL 33326, NDC 60505-1003-2Lack of Assurance of Sterility
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Supplement Interactions (1)
These dietary supplements may interact with Ketorolac. Always consult your healthcare provider.
- moderate
Check interactions with Ketorolac:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.