Lidocaine: Uses, Side Effects, and Drug Interactions
Brand names: DCH Hemorrhoidal
# Lidocaine Overview Lidocaine is a medicine that numbs pain in your skin and the area around it. Doctors and dentists use it to stop pain during small procedures like removing stitches, treating minor cuts, or doing dental work. It works by blocking pain signals in your nerves, so you don't feel as much discomfort. You can find lidocaine in different forms, like creams, sprays, or injections. It works pretty quickly and is commonly used because it's safe and effective when used the right way. There are some important safety rules to follow when using lidocaine. Never use more of the medicine than your doctor tells you to use, because too much can cause serious problems. Keep lidocaine away from children because it's dangerous if they swallow it or use too much. Don't use it on large areas of skin, near your eyes, or on broken or irritated skin unless your doctor says it's okay. If you're pregnant or breastfeeding, talk to your doctor before using lidocaine. If you have any side effects like swelling, difficulty breathing, or feeling dizzy or confused after using it, stop using it and call your doctor right away.
Taking Lidocaine with other medications?
Check Lidocaine against any other medication — the form below is already pre-filled.
Check Now ↓Most Reported Side Effects (FAERS)
- DRUG INEFFECTIVE12,935 reports
- PAIN5,015 reports
- OFF LABEL USE4,996 reports
- NAUSEA4,689 reports
- FATIGUE4,612 reports
- HEADACHE4,224 reports
- PRODUCT QUALITY ISSUE3,893 reports
- PRODUCT ADHESION ISSUE3,486 reports
- DYSPNOEA3,455 reports
- CONDITION AGGRAVATED3,143 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (5)
- Class II
Fresenius Kabi USA, LLC · July 16, 2026
Xylocaine (lidocaine HCl Injection, USP), 1%, 200 mg per 20 mL (10 mg per mL), 25 Multiple-Dose Vials, 20 mL, Rx only, Sterile, Fresenius Kabi, Lake Zurich, IL 60047 NDC Tray: 63323-485-27; NDC Vial:Presence of Particulate Matter: Hair was found in products
- Class II
Fresenius Kabi USA, LLC · July 16, 2026
Lidocaine HCl Injection, USP, 2%, 100 mg per 5 mL (20 mg per mL), 25 Single Dose Vials, 5 mL per vial, Rx only, Sterile, Fresenius Kabi, Lake Zurich, IL 60047 NDC Tray: 63323-208-05; NDC Vial: 63323Presence of Particulate Matter: Hair was found in products
- Class II
Fresenius Kabi USA, LLC · July 16, 2026
Xylocaine (lidocaine HCl Injection, USP), 1%, 500 mg per 50 mL (10 mg per mL), 25 Multiple-Dose Vials, 50 mL, Rx only, Sterile, Fresenius Kabi, Lake Zurich, IL 60047 NDC Tray: 63323-485-57; NDC Vial:Presence of Particulate Matter: Hair was found in products
- Class III
Asclemed USA Inc. · July 15, 2026
Lidolog Kit, Kit Contains: Lidocaine HCl Injection, USP, 2% (2mL) vial, 1 Dose, Single use Only, Rx Only, Distributed by: Enovachem Pharmaceuticals, Torrance, CA 90501, NDC: 76420-760-01.Labeling: Not Elsewhere Classified: The label wrap covers the barcode, making it hard to scan
- Class II
Asclemed USA Inc. · June 8, 2026
Accucaine, Kit contains: Lidocaine HCl Injection USP, 1% (10 mg/mL), 5 mL single dose ampule, Rx Only, Distributed by Enovachem Pharmaceuticals, Torrance, CA 90501, NDC: 76420-715-01.Lack of Assurance of Sterility
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Check interactions with Lidocaine:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.