lisinopril

Brand names: Lisinopril and Hydrochlorothiazide

# Lisinopril: What You Should Know Lisinopril is a medicine used to help control high blood pressure and treat heart problems. It works by relaxing blood vessels so blood can flow more easily through your body, which lowers your blood pressure. Doctors may prescribe this medicine to patients whose hearts aren't pumping as well as they should, or to help prevent heart damage. It's an important medication that helps reduce the risk of heart attacks and strokes by keeping your blood pressure at a healthy level. While lisinopril is helpful for many people, there are some important safety things to know. You should tell your doctor about all other medicines you take, especially water pills (diuretics), because taking lisinopril with these can sometimes cause your blood pressure to drop too low. Common side effects include dizziness, tiredness, or a dry cough—most of these are mild. You shouldn't take lisinopril if you're pregnant, as it can harm your baby. It's important to take this medicine exactly as your doctor prescribes, check your blood pressure regularly, and talk to your doctor before stopping the medication or making any changes.

Known Interactions

Drug Interactions Lisinopril Hypotension - Patients on Diuretic Therapy: Patients on diuretics and especially those in whom diuretic therapy was recently instituted, may occasionally experience an excessive reduction of blood pressure after initiation of therapy with lisinopril. The possibility of hypotensive effects with lisinopril can be minimized by either discontinuing the diuretic or increasing the salt intake prior to initiation of treatment with lisinopril. If it is necessary to continue the diuretic, initiate therapy with lisinopril at a dose of 5 mg daily, and provide close medical supervision after the initial dose for at least two hours and until blood pressure has stabilized for at least an additional hour. (See WARNINGS , and DOSAGE AND ADMINISTRATION .) When a diuretic is added to the therapy of a patient receiving lisinopril, an additional antihypertensive effect is usually observed (See DOSAGE AND ADMINISTRATION .) Non-steroidal Anti-inflammatory Agents Including Select

Source: FDA-approved drug labeling via openFDA

Most Reported Side Effects (FAERS)

  • FATIGUE19,929 reports
  • NAUSEA18,606 reports
  • DRUG INEFFECTIVE17,692 reports
  • DIARRHOEA17,298 reports
  • DYSPNOEA14,032 reports
  • PAIN13,723 reports
  • DIZZINESS13,631 reports
  • HEADACHE12,998 reports
  • ASTHENIA10,998 reports
  • VOMITING10,936 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

Check interactions with lisinopril:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.