Lorazepam: Uses, Side Effects, and Drug Interactions
Brand names: Lorazepam
# Lorazepam: What You Need to Know Lorazepam is a prescription medicine used to treat anxiety disorders and to help people relax before surgery or medical procedures. It works by slowing down activity in the brain and nervous system, which helps calm racing thoughts and reduces feelings of worry. Doctors may also prescribe it to help people sleep better or to stop seizures. This medication belongs to a group of drugs called benzodiazepines, and it usually starts working within 15 to 30 minutes of taking it. While lorazepam can be helpful, it's important to use it safely. Never mix this medicine with opioid painkillers (like codeine or morphine) without talking to your doctor first, because together they can make it harder to breathe. Don't drive, operate machinery, or do anything requiring alertness until you know how this drug affects you. This medicine can be habit-forming, so take it exactly as your doctor prescribes and don't suddenly stop taking it without medical guidance. Tell your doctor about all other medicines you take, and let them know if you're pregnant, breastfeeding, or have liver or kidney problems. If you experience severe drowsiness, confusion, or trouble breathing, seek emergency care right away.
Known Interactions (2)
Taking Lorazepam with other medications?
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Check Now ↓Most Reported Side Effects (FAERS)
- FATIGUE13,460 reports
- NAUSEA13,333 reports
- DRUG INEFFECTIVE12,118 reports
- DIARRHOEA10,356 reports
- OFF LABEL USE10,151 reports
- DYSPNOEA9,235 reports
- ANXIETY8,840 reports
- HEADACHE8,662 reports
- PAIN8,644 reports
- VOMITING8,562 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (4)
- Class II
Hikma Pharmaceuticals USA Inc. · July 22, 2025
Lorazepam Injection, USP, 2 mg/mL, 25 x 1mL vials/carton, Rx Only, Manufactured by: Hikma Berkeley Heights, NJ 07922, NDC# 0641-6044-25Failed Impurities/Degradation Specifications: An out-of-Specification for total related compounds
- Class II
The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories · January 21, 2025
Lorazepam Tablets, USP, 1mg, Unit Dose, 100 tablets per carton (10 x 10 blister packs), Rx only, The drug product contained in this package is from NDC # 69315-905 Leading Pharma, LLC., Packaged and DFailed impurities/degradation specifications and Sub-potent Drug: Out-of-specification results were obtained during routine stability testing for Assay and Impurities.
- Class II
The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories · January 21, 2025
Lorazepam Tablets, USP, 0.5mg, Unit Dose, 100 tablets per carton (10 x 10 blister packs), Rx only, The drug product contained in this package is from NDC # 69315-904 Leading Pharma, LLC., Packaged andFailed impurities/degradation specifications and Sub-potent Drug: Out-of-specification results were obtained during routine stability testing for Assay and Impurities.
- Class II
The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories · January 21, 2025
Lorazepam Tablets, USP, 2mg, Unit Dose, 100 tablets per carton (10 x 10 blister packs), Rx only, The drug product contained in this package is from NDC # 69315-906 Leading Pharma, LLC., Packaged and DFailed impurities/degradation specifications and Sub-potent Drug: Out-of-specification results were obtained during routine stability testing for Assay and Impurities.
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Supplement Interactions (2)
These dietary supplements may interact with Lorazepam. Always consult your healthcare provider.
- moderate
- mild
Check interactions with Lorazepam:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.