Metformin: Uses, Side Effects, and Drug Interactions
Brand names: ZITUVIMET
# Metformin Overview Metformin is a medication used to help control type 2 diabetes by lowering blood sugar levels. It works by reducing the amount of sugar your liver makes and helping your body use insulin more effectively. Doctors often prescribe metformin as the first medicine to try when someone is diagnosed with type 2 diabetes. It comes in tablet form and is usually taken by mouth, one or more times a day with meals. When taking metformin, there are some important safety points to remember. You should not take it if you have severe kidney problems or certain metabolic conditions. While taking metformin, avoid combining it with certain other medicines, especially carbonic anhydrase inhibitors (used for some eye conditions), since this combination can increase the risk of a serious condition called lactic acidosis. Make sure your doctor knows all the medicines you take and monitor your health regularly. Common side effects may include stomach upset or nausea, but these often go away over time. If you have questions about whether metformin is right for you or how to take it safely, always talk to your doctor or pharmacist.
Known Interactions (4)
Taking Metformin with other medications?
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Check Now ↓Most Reported Side Effects (FAERS)
- NAUSEA29,224 reports
- BLOOD GLUCOSE INCREASED27,329 reports
- DIARRHOEA27,194 reports
- DRUG INEFFECTIVE22,101 reports
- FATIGUE20,851 reports
- VOMITING18,771 reports
- LACTIC ACIDOSIS18,407 reports
- ACUTE KIDNEY INJURY17,472 reports
- WEIGHT DECREASED17,203 reports
- DYSPNOEA16,221 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (2)
- Class II
A-S Medication Solutions LLC · February 25, 2025
METFORMIN HYDROCHLORIDE EXTENDED- RELEASE 500MG, 180 TABLETS, Packaged BY: A-S Medication Solutions, Libertyville, IL 60048 NDC 50090-1494-3.Presence of Foreign Tablets/Capsules.
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Supplement Interactions (1)
These dietary supplements may interact with Metformin. Always consult your healthcare provider.
- mildginseng
Ginseng may lower blood sugar, potentially enhancing the effect of diabetes medications.
Monitor blood sugar levels more frequently.
Check interactions with Metformin:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.