Metoprolol: Uses, Side Effects, and Drug Interactions
Brand names: Metoprolol Tartrate
# Metoprolol: What You Need to Know Metoprolol is a medication called a beta-blocker that helps treat high blood pressure and heart problems. It works by slowing down your heart rate and making your heart pump with less force, which takes pressure off your blood vessels. This helps your heart work more efficiently and can prevent serious health issues like heart attacks and strokes. Your doctor might prescribe metoprolol if you have high blood pressure, chest pain, or a weak heart. Like all medicines, metoprolol can interact with other drugs and has some important safety rules. You should never stop taking it suddenly without talking to your doctor, as this can cause serious problems. Be careful if you're taking other heart medications, as metoprolol can interact with them and slow your heart rate too much. If you have an allergic reaction, tell emergency responders you're taking metoprolol because it might affect how certain emergency medicines work. Always tell your doctor about all other medicines and supplements you take, and follow the dosage instructions exactly as prescribed.
Known Interactions (3)
Taking Metoprolol with other medications?
Check Metoprolol against any other medication — the form below is already pre-filled.
Check Now ↓Most Reported Side Effects (FAERS)
- FATIGUE22,536 reports
- DYSPNOEA19,528 reports
- DIARRHOEA19,148 reports
- NAUSEA18,957 reports
- DRUG INEFFECTIVE17,046 reports
- DIZZINESS16,171 reports
- OFF LABEL USE14,092 reports
- DEATH13,701 reports
- ASTHENIA13,099 reports
- PAIN12,868 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (5)
- Class II
Teva Pharmaceuticals USA, Inc · January 29, 2026
Metoprolol Succinate Extended-Release Tablets, 200 mg, 100 tablets bottles, Rx Only, Teva Pharmaceuticals, Parsippany, NJ 07054, NDC: 45963-678-11Failed Dissolution Specifications
- Class II
Teva Pharmaceuticals USA, Inc · January 29, 2026
Metoprolol Succinate Extended-Release Tablets, 50 mg, 100 tablets bottles (NDC: 45963-676-11) and 1,000 tablets bottles (NDC: 45963-676-96), Rx Only, Teva Pharmaceuticals, Parsippany, NJ 07054Failed Dissolution Specifications
- Class II
Teva Pharmaceuticals USA, Inc · January 29, 2026
Metoprolol Succinate Extended-Release Tablets, 25 mg, 100 tablets bottles (NDC: 45963-709-11) and 1,000 tablets bottles (NDC: 45963-709-96), Rx Only, Teva Pharmaceuticals, Parsippany, NJ 07054Failed Dissolution Specifications
- Class II
Teva Pharmaceuticals USA, Inc · January 29, 2026
Metoprolol Succinate Extended-Release Tablets, Rx Only, 100 mg, 100 tablets bottles (NDC: 45963-677-11) and 1,000 tablets bottles (NDC: 45963-677-96), Teva Pharmaceuticals, Parsippany, NJ 07054.Failed Dissolution Specifications
- Class II
Westminster Pharmaceuticals LLC · August 6, 2025
Metoprolol Tartrate Tablets, USP, 50 mg, 1000 Tablets, Rx Only, Manufactured by: Renata PLC (General Plant -2), Noyapara, Bhawal Mirzapur, Rajendrapur, Gazipur, 1700 Bangladesh, Distributed by: WestmiCGMP Deviations: Presence of a nitrosamine, N-nitroso-metoprolol above the established Acceptable Daily Intake (ADI) level.
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
Supplement Interactions (1)
These dietary supplements may interact with Metoprolol. Always consult your healthcare provider.
- mildmelatonin
Melatonin may enhance the blood pressure-lowering effect of antihypertensives.
Monitor blood pressure when starting melatonin.
Check interactions with Metoprolol:
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.