Morphine: Uses, Side Effects, and Drug Interactions
Brand names: MORPHINE SULFATE
# Morphine: What You Need to Know Morphine is a powerful pain medication that doctors use to treat moderate to severe pain, especially in patients who have been seriously injured, had surgery, or have cancer. It works by changing the way your body feels and responds to pain. Morphine comes in different forms, including tablets, liquids, and extended-release versions that slowly release medicine over time. Because morphine is very strong, it should only be used exactly as a doctor prescribes it. Morphine is a controlled substance, which means the government carefully monitors its use because people can become dependent on it if they take it for too long or use it incorrectly. It's very important not to mix morphine with alcohol or other drugs that make you sleepy or drowsy, like certain anxiety medications, because this combination can be extremely dangerous and even life-threatening. Common side effects include drowsiness, constipation, and nausea. Always tell your doctor about all the medications you take, and never share your morphine with anyone else, even if they have similar pain. If you have questions about your morphine prescription, talk to your pharmacist or doctor—never change how much you take or how often you take it without their permission.
Taking Morphine with other medications?
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Check Now ↓Most Reported Side Effects (FAERS)
- DRUG DEPENDENCE33,820 reports
- PAIN26,762 reports
- OVERDOSE25,312 reports
- DEATH21,503 reports
- EMOTIONAL DISTRESS17,585 reports
- TOXICITY TO VARIOUS AGENTS15,711 reports
- DRUG WITHDRAWAL SYNDROME14,570 reports
- DRUG HYPERSENSITIVITY12,383 reports
- NAUSEA10,554 reports
- DRUG INEFFECTIVE9,370 reports
Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.
Recent Recalls (3)
- Class III
Winder Laboratories, LLC · November 26, 2025
Morphine Sulfate Oral Solution 100 mg / 5 mL (20 mg* / mL), 30 mL, Rx Only, For Oral Use Only, Manufactured By: /winder Laboratories, LLC, Winder, GA 30680. NDC: 75826-131-01Correct Labeled Product Mispack-Size stated on carton label did not match the size of the bottle in the carton.
- Class II
SUN PHARMACEUTICAL INDUSTRIES INC · February 6, 2025
Morphine Sulfate Extended-Release Tablets, 100 mg, 100-count bottles, Rx Only, Manufactured by: Ohm Laboratories Inc., New Brunswick, NJ 08901. Distributed by: Sun Pharmaceutical Industries, Inc., CrFailed Dissolution Specifications
- Class II
Hikma Pharmaceuticals USA Inc. · March 12, 2024
Infumorph (Preservative-free Morphine Sulfate Sterile Solution), 20 mL ampul, Rx only, Manufactured by Hikma Berkeley Heights, NJ 07922, NDC 0641-6039-01The filter included in the carton has an expiration date that has expired prior to the expiration date of the actual product lot.
Source: FDA (openFDA Drug Enforcement). Voluntary and mandated recalls affecting this drug.
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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.