nebivolol

Brand names: Nebivolol

# Nebivolol: What You Need to Know Nebivolol is a medicine used to treat high blood pressure. It works by helping your heart beat more slowly and with less force, which allows your blood vessels to relax and makes it easier for blood to flow through them. When you take this medication as prescribed by your doctor, it helps keep your blood pressure at a healthier level. This can reduce your risk of serious health problems like heart attacks and strokes. Before taking nebivolol, it's important to tell your doctor about all the other medications you're taking, because some drugs can interact with it in unsafe ways. For example, certain medicines that slow your heart rate or lower your blood pressure could cause problems when combined with nebivolol. You should never suddenly stop taking this medicine without talking to your doctor first, as that can cause your blood pressure to spike dangerously. Common side effects might include dizziness, fatigue, or headaches, but your doctor can help you manage these. Always take nebivolol exactly as your doctor directs and report any concerning symptoms right away.

Known Interactions

7 DRUG INTERACTIONS CYP2D6 enzyme inhibitors may increase nebivolol levels ( 7.1 ) Reserpine or clonidine may produce excessive reduction of sympathetic activity. ( 7.2 ) Both digitalis glycosides and β-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can increase the risk of bradycardia. ( 7.3 ) Verapamil- or diltiazem-type calcium channel blockers may cause excessive reductions in heart rate, blood pressure, and cardiac contractility. ( 7.4 ) 7.1 CYP2D6 Inhibitors Use caution when nebivolol is co-administered with CYP2D6 inhibitors (quinidine, propafenone, fluoxetine, paroxetine, etc.) [ see Clinical Pharmacology ( 12.5 ) ]. 7.2 Hypotensive Agents Do not use nebivolol tablets with other β-blockers. Closely monitor patients receiving catecholamine-depleting drugs, such as reserpine or guanethidine, because the added β-blocking action of nebivolol may produce excessive reduction of sympathetic activity. In patients who are receiving nebivolol and cloni

Source: FDA-approved drug labeling via openFDA

Most Reported Side Effects (FAERS)

  • FATIGUE1,808 reports
  • DIARRHOEA1,748 reports
  • DYSPNOEA1,681 reports
  • DRUG INEFFECTIVE1,591 reports
  • NAUSEA1,572 reports
  • HEADACHE1,399 reports
  • DIZZINESS1,360 reports
  • ACUTE KIDNEY INJURY1,267 reports
  • OFF LABEL USE1,224 reports
  • ASTHENIA1,073 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

Check interactions with nebivolol:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.