olmesartan

Brand names: olmesartan medoxomil-hydrochlorothiazide

# Overview of Olmesartan Olmesartan is a medication used to treat high blood pressure. When you have high blood pressure, your blood pushes too hard against your blood vessel walls, which can damage your heart and organs over time. Olmesartan works by relaxing your blood vessels so blood can flow more easily, bringing your blood pressure down to a healthier level. This helps protect your heart, brain, and kidneys from damage caused by high blood pressure. Before taking olmesartan, it's important to know some safety information. Tell your doctor about all medications you take, especially blood thinners, water pills, pain relievers, and diabetes medicines, because olmesartan can interact with them. Olmesartan should not be taken during pregnancy because it can harm an unborn baby. Some people may experience side effects like dizziness, tiredness, or stomach problems. You should never take olmesartan if you're allergic to it, and you need regular check-ups with your doctor to make sure the medication is working safely for you.

Known Interactions

7 DRUG INTERACTIONS Lithium: Risk of lithium toxicity ( 7.2 ) Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic and antihypotensive effects; increased risk of renal toxicity ( 7.3 ) Dual inhibition of the renin-angiotensin system: Increased risk of renal impairment, hypotension, and hyperkalemia ( 7.4 ) Colesevelam hydrochloride: Consider administering olmesartan at least 4 hours before colesevelam hydrochloride dose ( 7.5 ) Antidiabetic drugs: Dosage adjustment may be required ( 7.6 ) Cholestyramine and colestipol: Reduced absorption of thiazides ( 7.6 ) 7.1 Agents Increasing Serum Potassium Coadministration of olmesartan medoxomil and hydrochlorothiazide with other drugs that raise serum potassium levels may result in hyperkalemia. Monitor serum potassium in such patients. 7.2 Lithium Increases in serum lithium concentrations and lithium toxicity have been reported during concomitant administration of lithium with angiotensin II receptor antagonists or hyd

Source: FDA-approved drug labeling via openFDA

Most Reported Side Effects (FAERS)

  • SPRUE-LIKE ENTEROPATHY4,192 reports
  • DIARRHOEA2,990 reports
  • WEIGHT DECREASED2,699 reports
  • DIZZINESS2,563 reports
  • GASTROOESOPHAGEAL REFLUX DISEASE2,542 reports
  • NAUSEA2,469 reports
  • DRUG INEFFECTIVE2,391 reports
  • ACUTE KIDNEY INJURY2,358 reports
  • FATIGUE2,030 reports
  • HEADACHE1,730 reports

Source: FDA Adverse Event Reporting System (FAERS). Voluntary reports do not establish causation.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.