Vitamin E and Aspirin: Can You Take Them Together?

Here's what FDA drug labeling and NIH supplement data show.

MODERATE

Interaction Found

What happens: High-dose vitamin E (>400 IU) may inhibit platelet aggregation and enhance anticoagulant effects.

What to do: Avoid high-dose vitamin E with blood thinners.

Source: FDA-approved drug labeling and NIH Office of Dietary Supplements fact sheets.

Learn more

Aspirin — full safety profile, side effects, and all known interactions.

Vitamin E — supplement labels containing this ingredient.

Frequently asked questions

Can I take Vitamin E with Aspirin?

Avoid high-dose vitamin E with blood thinners.

What happens if you take Vitamin E and Aspirin together?

High-dose vitamin E (>400 IU) may inhibit platelet aggregation and enhance anticoagulant effects.

What should I do if I take both?

Avoid high-dose vitamin E with blood thinners. Always consult your healthcare provider before combining supplements and medications.

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.