Melatonin and Atenolol: Can You Take Them Together?

Here's what FDA drug labeling and NIH supplement data show.

MILD

Interaction Found

What happens: Melatonin may enhance the blood pressure-lowering effect of antihypertensives.

What to do: Monitor blood pressure when starting melatonin.

Source: FDA-approved drug labeling and NIH Office of Dietary Supplements fact sheets.

Learn more

Atenolol — full safety profile, side effects, and all known interactions.

Melatonin — supplement labels containing this ingredient.

Frequently asked questions

Can I take Melatonin with Atenolol?

Monitor blood pressure when starting melatonin.

What happens if you take Melatonin and Atenolol together?

Melatonin may enhance the blood pressure-lowering effect of antihypertensives.

What should I do if I take both?

Monitor blood pressure when starting melatonin. Always consult your healthcare provider before combining supplements and medications.

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.