Melatonin and Clonazepam: Can You Take Them Together?
Here's what FDA drug labeling and NIH supplement data show.
Interaction Found
What happens: Additive sedation effect.
What to do: Use caution when combining. Start with low melatonin dose.
Source: FDA-approved drug labeling and NIH Office of Dietary Supplements fact sheets.
Learn more
Clonazepam — full safety profile, side effects, and all known interactions.
Melatonin — supplement labels containing this ingredient.
Frequently asked questions
Can I take Melatonin with Clonazepam?
Use caution when combining. Start with low melatonin dose.
What happens if you take Melatonin and Clonazepam together?
Additive sedation effect.
What should I do if I take both?
Use caution when combining. Start with low melatonin dose. Always consult your healthcare provider before combining supplements and medications.
SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.