Clopidogrel and Diclofenac: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking clopidogrel (a blood thinner) with diclofenac (a pain reliever) increases your bleeding risk. Both drugs affect how your blood clots, which can cause more bleeding than expected.

What to do: Talk to your doctor or pharmacist before taking these medicines together. Do not stop either medication without speaking to your doctor first. Your doctor may monitor you more closely or suggest a different pain reliever that is safer to use with clopidogrel.

Source: FDA-approved drug labeling via openFDA

About These Medications

Clopidogrel — View full safety profile, side effects, and all known interactions.

Diclofenac — View full safety profile, side effects, and all known interactions.

Other interactions with Clopidogrel

SEVEREwarfarinMODERATEomeprazoleMODERATEpantoprazoleMODERATEibuprofenMODERATEtrazodoneMODERATEnaproxen

Other interactions with Diclofenac

SEVEREwarfarinMODERATEhydrochlorothiazideMODERATElosartanMODERATEescitalopramMODERATEsertralineMODERATEnaproxen

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.