Vitamin D and Digoxin: Can You Take Them Together?

Here's what FDA drug labeling and NIH supplement data show.

MODERATE

Interaction Found

What happens: Vitamin D increases calcium absorption, which can increase the risk of digoxin toxicity (arrhythmias).

What to do: Monitor calcium and digoxin levels.

Source: FDA-approved drug labeling and NIH Office of Dietary Supplements fact sheets.

Learn more

Digoxin — full safety profile, side effects, and all known interactions.

Vitamin D — supplement labels containing this ingredient.

Frequently asked questions

Can I take Vitamin D with Digoxin?

Monitor calcium and digoxin levels.

What happens if you take Vitamin D and Digoxin together?

Vitamin D increases calcium absorption, which can increase the risk of digoxin toxicity (arrhythmias).

What should I do if I take both?

Monitor calcium and digoxin levels. Always consult your healthcare provider before combining supplements and medications.

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.