Alprazolam and Clonazepam: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

SEVERE

Interaction Found

Taking alprazolam and clonazepam together is dangerous. Both drugs slow your brain and breathing. Using them together can cause serious breathing problems, extreme drowsiness, and other harmful effects. The risk gets even worse if you also take opioid painkillers or other medicines that slow your brain.

What to do: Tell your doctor about all medicines you take. Do not stop any medicine on your own. Your doctor will decide if it's safe to use these drugs together or if you need different medicines.

Source: FDA-approved drug labeling via openFDA

About These Medications

Alprazolam — View full safety profile, side effects, and all known interactions.

Clonazepam — View full safety profile, side effects, and all known interactions.

Other interactions with Alprazolam

SEVERElorazepamSEVEREtramadolMODERATElosartanMODERATEfluoxetineMODERATEwarfarinMODERATEvenlafaxine

Other interactions with Clonazepam

MODERATEescitalopramMILDlosartanMILDsertralineMILDfluoxetine

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.