Clonazepam and Fluoxetine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MILD

Interaction Found

Taking clonazepam and fluoxetine together is generally safe. Studies show fluoxetine does not significantly change how your body processes clonazepam. However, both medicines can cause drowsiness, so you may feel extra sleepy or tired when taking them together.

What to do: Talk to your doctor or pharmacist about how you're feeling. Don't stop taking either medicine on your own. Let your doctor know if you experience excessive drowsiness, dizziness, or difficulty concentrating.

Source: FDA-approved drug labeling via openFDA

About These Medications

Clonazepam — View full safety profile, side effects, and all known interactions.

Fluoxetine — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.