Alprazolam and Lorazepam: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

SEVERE

Interaction Found

Alprazolam and lorazepam are both brain-calming medicines. Taking them together is dangerous because they can cause serious side effects like extreme drowsiness, trouble breathing, and slowed heart rate. This risk gets even worse if you also take pain medicines like opioids.

What to do: Tell your doctor about all medicines you take, especially pain relievers, sleeping pills, and other calming drugs. Do not stop taking any medicine on your own. Your doctor will decide the safest way to treat you.

Source: FDA-approved drug labeling via openFDA

About These Medications

Alprazolam — View full safety profile, side effects, and all known interactions.

Lorazepam — View full safety profile, side effects, and all known interactions.

Other interactions with Alprazolam

SEVEREclonazepamSEVEREtramadolMODERATElosartanMODERATEfluoxetineMODERATEwarfarinMODERATEvenlafaxine

Other interactions with Lorazepam

MODERATElosartanMILDduloxetine

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.