Clopidogrel and Naproxen: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking clopidogrel with naproxen increases your risk of bleeding. Naproxen is a pain reliever that can thin your blood when combined with clopidogrel, a blood thinner. This means you could bleed more easily or have serious bleeding problems.

What to do: Talk to your doctor or pharmacist before taking naproxen or other NSAIDs with clopidogrel. Your doctor may suggest a different pain reliever or adjust your medications. Do not stop taking either medicine without talking to your doctor first.

Source: FDA-approved drug labeling via openFDA

About These Medications

Clopidogrel — View full safety profile, side effects, and all known interactions.

Naproxen — View full safety profile, side effects, and all known interactions.

Other interactions with Clopidogrel

SEVEREwarfarinSEVEREaspirinMODERATEibuprofenMODERATEomeprazoleMODERATEpantoprazoleMODERATEtrazodone

Other interactions with Naproxen

SEVEREwarfarinMODERATEpropranololMODERATEsertralineMODERATEvenlafaxineMODERATEaspirinMILDtrazodone

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.