Naproxen and Venlafaxine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking naproxen and venlafaxine together increases your risk of bleeding problems. These medicines can affect how your blood clots, making you more likely to bruise easily or bleed longer than normal.

What to do: Watch for signs of unusual bleeding or bruising. Tell your doctor right away if you notice blood in your stool or urine, nosebleeds, or bleeding gums. Do not stop taking either medicine without talking to your doctor first. Your doctor may need to monitor you or adjust your doses.

Source: FDA-approved drug labeling via openFDA

About These Medications

Naproxen — View full safety profile, side effects, and all known interactions.

Venlafaxine — View full safety profile, side effects, and all known interactions.

Other interactions with Naproxen

SEVEREwarfarinMODERATEsertralineMODERATEpropranololMODERATElisinoprilMODERATEcitalopramMILDtrazodone

Other interactions with Venlafaxine

MODERATEwarfarinMODERATEmetoprololMODERATEescitalopramMODERATEsertralineMODERATEcitalopramMODERATEbupropion

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.