Amoxicillin and Simvastatin: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking amoxicillin with simvastatin may increase the risk of muscle pain and damage. This happens because amoxicillin can change how your body breaks down simvastatin.

What to do: Talk to your doctor or pharmacist before taking these medicines together. Do not stop either medicine without talking to your doctor first. Your doctor may need to watch you more carefully or adjust your doses.

Source: FDA-approved drug labeling via openFDA

About These Medications

Amoxicillin — View full safety profile, side effects, and all known interactions.

Simvastatin — View full safety profile, side effects, and all known interactions.

Other interactions with Amoxicillin

MODERATEdoxycyclineMODERATEoxycodoneMODERATEtramadolMILDfluoxetineMILDfurosemideMILDpravastatin

Other interactions with Simvastatin

MODERATEwarfarinMODERATEamlodipineMODERATEatorvastatinMODERATEdoxycyclineMODERATEpravastatinMODERATErosuvastatin

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.