Amoxicillin and Fluoxetine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MILD

Interaction Found

Amoxicillin and fluoxetine can interact in your body. Fluoxetine may affect how amoxicillin works. This could reduce the antibiotic's effectiveness or cause unexpected side effects.

What to do: Tell your doctor and pharmacist that you take both medicines. They can monitor you for any problems. Do not stop either medication without talking to your doctor first.

Source: FDA-approved drug labeling via openFDA

About These Medications

Amoxicillin — View full safety profile, side effects, and all known interactions.

Fluoxetine — View full safety profile, side effects, and all known interactions.

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.