Citalopram and Fluoxetine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking citalopram with fluoxetine together can cause serotonin syndrome, which is a serious condition with symptoms like confusion, rapid heartbeat, and muscle stiffness. This combination can also increase your risk of bleeding, especially if you take blood thinners like warfarin.

What to do: Talk to your doctor before taking these medicines together. Don't stop either medication on your own. Your doctor may adjust your doses or watch you more closely. Tell your doctor if you take blood thinners so they can monitor you for bleeding risks.

Source: FDA-approved drug labeling via openFDA

About These Medications

Citalopram — View full safety profile, side effects, and all known interactions.

Fluoxetine — View full safety profile, side effects, and all known interactions.

Other interactions with Citalopram

SEVEREescitalopramMODERATEnaproxenMODERATEsertralineMODERATEduloxetineMODERATEmeloxicamMODERATEvenlafaxine

Other interactions with Fluoxetine

MODERATEmetoprololMODERATElosartanMODERATEsertralineMODERATEtramadolMODERATEibuprofenMODERATEwarfarin

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.