Citalopram and Venlafaxine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking citalopram with venlafaxine together can cause serotonin syndrome, a serious condition with symptoms like confusion, rapid heartbeat, and muscle stiffness. These drugs can also increase bleeding risk, especially if you take blood thinners.

What to do: Tell your doctor about all medications you take, including blood thinners. Watch for signs of serotonin syndrome (confusion, fever, shaking) or unusual bleeding. Do not stop taking your medications without talking to your doctor first. Your doctor will decide if this combination is safe for you.

Source: FDA-approved drug labeling via openFDA

About These Medications

Citalopram — View full safety profile, side effects, and all known interactions.

Venlafaxine — View full safety profile, side effects, and all known interactions.

Other interactions with Citalopram

SEVEREescitalopramMODERATEnaproxenMODERATEsertralineMODERATEduloxetineMODERATEmeloxicamMODERATEfluoxetine

Other interactions with Venlafaxine

MODERATEwarfarinMODERATEmetoprololMODERATEescitalopramMODERATEsertralineMODERATEbupropionMODERATEibuprofen

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.