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fluoxetine and sertraline — Drug Interaction

Can you take fluoxetine and sertralinetogether? Here's what FDA data shows.

MODERATE

Interaction Found

Taking fluoxetine and sertraline together can cause problems because both drugs stick to proteins in your blood. When they compete for space, the levels of each drug in your body can change. This might make side effects worse or make the medicines less effective.

What to do: Talk to your doctor or pharmacist before taking these medicines together. Do not stop either medicine on your own. Your doctor may need to adjust your doses or watch you more carefully.

Source: FDA-approved drug labeling via openFDA

About These Medications

fluoxetine — View full safety profile, side effects, and all known interactions.

sertraline — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.