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fluoxetine and ibuprofen — Drug Interaction

Can you take fluoxetine and ibuprofentogether? Here's what FDA data shows.

MODERATE

Interaction Found

Taking fluoxetine with ibuprofen increases your risk of bleeding. This happens because ibuprofen thins your blood and fluoxetine makes this effect stronger. You may bruise easily, bleed longer from cuts, or have other bleeding problems.

What to do: Talk to your doctor or pharmacist before taking ibuprofen with fluoxetine. They may suggest a safer pain reliever. Do not stop either medication without talking to your doctor first.

Source: FDA-approved drug labeling via openFDA

About These Medications

fluoxetine — View full safety profile, side effects, and all known interactions.

ibuprofen — View full safety profile, side effects, and all known interactions.

Other interactions with fluoxetine

MODERATEmetoprololMODERATElosartanMODERATEsertralineMODERATEbupropionMODERATEtramadolMODERATEalprazolam

Other interactions with ibuprofen

MODERATElisinoprilMODERATElosartanMODERATEhydrochlorothiazideMODERATEsertralineMODERATEfurosemideMODERATEescitalopram

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.