Clonazepam and Tramadol: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

SEVERE

Interaction Found

Taking clonazepam and tramadol together can slow your breathing dangerously. Both drugs affect your brain in ways that can make it hard to breathe, especially when combined.

What to do: Talk to your doctor right away about taking both medicines. Don't stop either drug on your own. Your doctor may need to adjust doses or find alternatives. Watch for drowsiness or trouble breathing and call 911 if you can't breathe.

Source: FDA-approved drug labeling via openFDA

About These Medications

Clonazepam — View full safety profile, side effects, and all known interactions.

Tramadol — View full safety profile, side effects, and all known interactions.

Other interactions with Clonazepam

SEVEREoxycodoneMODERATEescitalopramMODERATEmontelukastMILDlosartanMILDsertralineMILDfluoxetine

Other interactions with Tramadol

MODERATEtrazodoneMODERATEwarfarinMODERATEvenlafaxineMODERATEomeprazoleMODERATElosartanMODERATEgabapentin

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.