Diclofenac and Fluoxetine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking diclofenac and fluoxetine together may increase the risk of bleeding and stomach problems. Fluoxetine can change how your body processes diclofenac, making side effects more likely.

What to do: Talk to your doctor or pharmacist before taking these medicines together. Don't stop either medication on your own. Your doctor may monitor you more closely or adjust your doses if needed.

Source: FDA-approved drug labeling via openFDA

About These Medications

Diclofenac — View full safety profile, side effects, and all known interactions.

Fluoxetine — View full safety profile, side effects, and all known interactions.

Other interactions with Diclofenac

SEVEREwarfarinMODERATEhydrochlorothiazideMODERATElosartanMODERATEescitalopramMODERATEsertralineMODERATEnaproxen

Other interactions with Fluoxetine

MODERATEmetoprololMODERATElosartanMODERATEsertralineMODERATEtramadolMODERATEibuprofenMODERATEwarfarin

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.