Escitalopram and Fluoxetine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking escitalopram and fluoxetine together can increase serotonin in your body too much. This can cause serotonin syndrome, which includes symptoms like confusion, rapid heartbeat, high fever, and muscle stiffness. These two drugs should not be taken together.

What to do: Tell your doctor if you're taking both medications. Do not stop taking either drug on your own. Your doctor will decide the safest way to adjust your medicines.

Source: FDA-approved drug labeling via openFDA

About These Medications

Escitalopram — View full safety profile, side effects, and all known interactions.

Fluoxetine — View full safety profile, side effects, and all known interactions.

Other interactions with Escitalopram

MODERATElosartanMODERATEvenlafaxineMODERATEibuprofenMODERATEmeloxicamMODERATEwarfarinMODERATEnaproxen

Other interactions with Fluoxetine

MODERATEmetoprololMODERATElosartanMODERATEsertralineMODERATEtramadolMODERATEibuprofenMODERATEwarfarin

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.