Escitalopram and Oxycodone: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking escitalopram with oxycodone together can cause a serious condition called serotonin syndrome. This means too much serotonin builds up in your body, causing confusion, rapid heartbeat, muscle stiffness, and fever.

What to do: Talk to your doctor before taking these medicines together. Tell them about all your medications. Watch for signs of serotonin syndrome. Never stop taking either medicine without talking to your doctor first.

Source: FDA-approved drug labeling via openFDA

About These Medications

Escitalopram — View full safety profile, side effects, and all known interactions.

Oxycodone — View full safety profile, side effects, and all known interactions.

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.