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fluoxetine and venlafaxine — Drug Interaction

Can you take fluoxetine and venlafaxinetogether? Here's what FDA data shows.

MODERATE

Interaction Found

Taking fluoxetine and venlafaxine together can increase serotonin levels in your body too much. This may cause confusion, muscle stiffness, rapid heartbeat, or fever. Certain stomach medicines (like cimetidine) can make venlafaxine levels higher in your blood.

What to do: Talk to your doctor or pharmacist before taking these medicines together. Tell them about all medicines and supplements you use, especially stomach medicines. Don't stop taking any medication without talking to your doctor first.

Source: FDA-approved drug labeling via openFDA

About These Medications

fluoxetine — View full safety profile, side effects, and all known interactions.

venlafaxine — View full safety profile, side effects, and all known interactions.

Other interactions with fluoxetine

MODERATEmetoprololMODERATElosartanMODERATEsertralineMODERATEbupropionMODERATEtramadolMODERATEibuprofen

Other interactions with venlafaxine

MODERATEmetoprololMODERATEbupropionMODERATEibuprofenMODERATEalprazolamMODERATEwarfarinMODERATEnaproxen

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.