Ibuprofen and Sertraline: Can You Take Them Together?
Here's what FDA-approved drug labeling shows.
MODERATE
Interaction Found
Ibuprofen and sertraline are both strongly attached to proteins in your blood. When taken together, they can compete for space and cause changes in how much of each drug is active in your body. This could make either medicine work differently than expected.
What to do: Talk to your doctor or pharmacist before taking ibuprofen with sertraline. They may suggest a different pain reliever or adjust your doses. Do not stop either medication without speaking to your doctor first.
Source: FDA-approved drug labeling via openFDA
About These Medications
Ibuprofen — View full safety profile, side effects, and all known interactions.
Sertraline — View full safety profile, side effects, and all known interactions.
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Other interactions with Sertraline
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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.