Fluoxetine and Meloxicam: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking fluoxetine and meloxicam together may increase your risk of bleeding. Meloxicam is an NSAID pain reliever that can thin your blood. Fluoxetine is an antidepressant that affects how your body clots. Combined, they work against each other and raise bleeding risk.

What to do: Talk to your doctor or pharmacist about this combination. Don't stop either medicine on your own. Your doctor may watch you more closely, adjust doses, or suggest a different pain reliever.

Source: FDA-approved drug labeling via openFDA

About These Medications

Fluoxetine — View full safety profile, side effects, and all known interactions.

Meloxicam — View full safety profile, side effects, and all known interactions.

Other interactions with Fluoxetine

MODERATEmetoprololMODERATElosartanMODERATEsertralineMODERATEtramadolMODERATEibuprofenMODERATEwarfarin

Other interactions with Meloxicam

SEVEREwarfarinMODERATEpropranololMODERATEnaproxenMODERATEtrazodoneMODERATEvenlafaxineMODERATEsertraline

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.