Meloxicam and Sertraline: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking meloxicam (a pain reliever) with sertraline (an antidepressant) together increases your risk of bleeding. This happens because sertraline affects how your blood clots. You may bleed more easily or have harder-to-stop bleeding.

What to do: Talk to your doctor about taking these medicines together. Watch for signs of unusual bleeding like nosebleeds, bruising, or blood in your urine or stool. Tell your doctor right away if you notice any of these signs. Do not stop taking either medicine without talking to your doctor first.

Source: FDA-approved drug labeling via openFDA

About These Medications

Meloxicam — View full safety profile, side effects, and all known interactions.

Sertraline — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.