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alprazolam and tramadol — Drug Interaction

Can you take alprazolam and tramadoltogether? Here's what FDA data shows.

SEVERE

Interaction Found

Taking alprazolam and tramadol together can be dangerous. Both drugs slow down your brain and nervous system. When combined, they can cause extreme drowsiness, difficulty breathing, loss of consciousness, and even death.

What to do: Talk to your doctor before taking these medicines together. Do not stop either medicine on your own. Your doctor may adjust your doses or suggest a safer alternative.

Source: FDA-approved drug labeling via openFDA

About These Medications

alprazolam — View full safety profile, side effects, and all known interactions.

tramadol — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.