Lorazepam and Oxycodone: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

SEVERE

Interaction Found

Taking lorazepam and oxycodone together can be dangerous. Both drugs slow down your breathing. When combined, your breathing can become dangerously slow or even stop. You may also feel very drowsy. Avoid alcohol and other sleep medicines, which make this risk worse.

What to do: Talk to your doctor before taking these drugs together. Your doctor may need to adjust your doses or watch you closely. Never stop either medicine without talking to your doctor first. Seek emergency help if you have trouble breathing or excessive drowsiness.

Source: FDA-approved drug labeling via openFDA

About These Medications

Lorazepam — View full safety profile, side effects, and all known interactions.

Oxycodone — View full safety profile, side effects, and all known interactions.

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.