Amoxicillin and Trazodone: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MILD

Interaction Found

Amoxicillin and trazodone can be taken together safely. Amoxicillin is an antibiotic that doesn't significantly interact with trazodone, a sleep medication. However, trazodone can make you feel drowsy or dizzy, especially when combined with alcohol or other sedating drugs.

What to do: Tell your doctor about all medications you take. Don't drink alcohol while on trazodone. Don't stop either medication without talking to your doctor first. Report any unusual drowsiness or dizziness to your healthcare provider.

Source: FDA-approved drug labeling via openFDA

About These Medications

Amoxicillin — View full safety profile, side effects, and all known interactions.

Trazodone — View full safety profile, side effects, and all known interactions.

Other interactions with Amoxicillin

MODERATEtramadolMODERATEoxycodoneMODERATEwarfarinMODERATEdoxycyclineMILDfluoxetine

Other interactions with Trazodone

SEVEREoxycodoneMODERATEwarfarinMODERATElosartanMODERATEtramadolMILDibuprofenMILDnaproxen

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.