Aspirin and Sertraline: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Aspirin and sertraline are both tightly attached to proteins in your blood. When taken together, they can compete for those spots, which might cause the level of one or both drugs to change in your body. This could make either drug work differently than expected.

What to do: Tell your doctor that you take both aspirin and sertraline. Your doctor may check your blood work or adjust your doses. Don't stop taking either medication on your own—talk to your doctor first about any concerns.

Source: FDA-approved drug labeling via openFDA

About These Medications

Aspirin — View full safety profile, side effects, and all known interactions.

Sertraline — View full safety profile, side effects, and all known interactions.

Other interactions with Aspirin

MODERATElisinoprilMODERATElosartanMODERATEhydrochlorothiazideMODERATElevothyroxineMODERATEfurosemideMODERATEatenolol

Other interactions with Sertraline

MODERATEvenlafaxineMODERATEwarfarinMODERATEatenololMODERATEbupropionMODERATEcitalopramMILDclonazepam

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.